Crizotinib hydrochloride (PF-02341066 hydrochloride) |

规格	库存	目录价	会员专享价	数量
10 mg	3-5days	￥600.00	登录后可见	- +
25 mg	3-5days	￥980.00	登录后可见	- +
50 mg	3-5days	￥1568.00	登录后可见	- +

规格

库存

目录价

会员专享价

数量

10 mg

3-5days

￥600.00

登录后可见

- +

25 mg

3-5days

￥980.00

登录后可见

- +

50 mg

3-5days

￥1568.00

登录后可见

- +

基本信息

英文名称	Crizotinib hydrochloride \| PF-02341066 hydrochloride
中文名称	盐酸克里唑替尼
CAS号	1415560-69-8
分子式	C21H23Cl3FN5O
分子量	486.80
外观	Yellow to brown powder
储存条件	4°C, sealed storage, away from moisture

产品详情

Crizotinib HCl (formerly known as PF-02341066 hydrochloride; trade name: Xalkori) is a potent, orally bioavailable small molecule inhibitor of c-Met and ALK, with IC50 values of 11 nM and 24 nM in assays involving cells, respectively. In the US, crizotinib is licensed for the treatment of non-small cell lung cancer (NSCLC). It is also being investigated in clinical trials for safety and effectiveness in the treatment of neuroblastoma, anaplastic large cell lymphoma, and other advanced solid tumors in both adults and children. Crizotinib inhibits the activation of the MET signaling pathway and the membrane receptor MET, which in susceptible tumor cell populations may prevent tumor cell growth, migration, invasion, and angiogenesis.

盐酸克里唑替尼

Crizotinib hydrochloride | PF-02341066 hydrochloride

化学品安全说明书(MSDS)