英文名称 | Afuresertib-F free base | Afuresertib-F free base | GSK-2110183-analog 1 |
---|---|
中文名称 | 阿氟瑞色替 |
CAS号 | 1047634-63-8 |
分子式 | C18H16Cl2F2N4OS |
分子量 | 445.31 |
储存条件 | -20°C, protect from light, stored under nitrogen |
英文名称 | Afuresertib-F free base | Afuresertib-F free base | GSK-2110183-analog 1 |
---|---|
中文名称 | 阿氟瑞色替 |
CAS号 | 1047634-63-8 |
分子式 | C18H16Cl2F2N4OS |
分子量 | 445.31 |
储存条件 | -20°C, protect from light, stored under nitrogen |
Afuresertib-F (GSK2110183) ian analog of Afuresertib, is a potent, orally bioavailable andATP-competitive Akt inhibitor with Ki of 0.08 nM, 2 nM, and 2.6 nM for Akt1, Akt2, and Akt3, respectively.