英文名称 | Afuresertib | GSK2110183 | LAE002 |
---|---|
中文名称 | 阿氟色替 |
CAS号 | 1047644-62-1 |
分子式 | C18H17Cl2FN4OS |
分子量 | 427.32 |
外观 | White to off-white powder |
储存条件 | -20°C, protect from light, stored under nitrogen |
英文名称 | Afuresertib | GSK2110183 | LAE002 |
---|---|
中文名称 | 阿氟色替 |
CAS号 | 1047644-62-1 |
分子式 | C18H17Cl2FN4OS |
分子量 | 427.32 |
外观 | White to off-white powder |
储存条件 | -20°C, protect from light, stored under nitrogen |
Afuresertib (GSK2110183) is an orally bioavailable, selective, ATP-competitive and potent pan-Akt kinase inhibitor with Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3, respectively.