Laduviglusib trihydrochloride | CHIR-99021 Trihydrochloride

规格	库存	目录价	会员专享价	数量
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规格

库存

目录价

会员专享价

数量

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基本信息

英文名称	Laduviglusib trihydrochloride \| CHIR-99021 Trihydrochloride
中文名称	CHIR-99021三盐酸盐 \| 拉格鲁西布三盐酸盐
CAS号	1782235-14-6
分子式	C22H18Cl2N8·3HCl
分子量	574.72
外观	White to light yellow powder
储存条件	4°C, sealed storage, away from moisture

产品详情

Laduviglusib (CHIR-99021) trihydrochloride is a potent and selective GSK-3α/β inhibitor with IC50s of 10 nM and 6.7 nM. Laduviglusib trihydrochloride shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases. Laduviglusib trihydrochloride is also a potent Wnt/β-catenin signaling pathway activator. Laduviglusib trihydrochloride enhances mouse and human embryonic stem cells self-renewal. Laduviglusib trihydrochloride induces autophagy.

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