Laduviglusib | CHIR-99021

规格	库存	目录价	会员专享价	数量
10 mg	In-stock	￥500.00	登录后可见	- +
25 mg	In-stock	￥886.00	登录后可见	- +
50 mg	In-stock	￥1568.00	登录后可见	- +

规格

库存

目录价

会员专享价

数量

10 mg

In-stock

￥500.00

登录后可见

- +

25 mg

In-stock

￥886.00

登录后可见

- +

50 mg

In-stock

￥1568.00

登录后可见

- +

基本信息

英文名称	Laduviglusib \| CHIR-99021 \| CT99021
中文名称	拉格鲁西布
CAS号	252917-06-9
分子式	C22H18Cl2N8
分子量	465.34
外观	Off-white to light brown powder
储存条件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

安全信息

化学稳定性	DMSO中的溶液可在-20°下稳定储存3个月。

产品详情

Laduviglusib (CHIR-99021, CT99021) is a GSK-3α and GSK-3β inhibitor with IC50 of 10 nM and 6.7 nM, respectively. CHIR99201 does not exhibit cross-reactivity against cyclin-dependent kinases (CDKs) and shows a 350-fold selectivity toward GSK-3β compared to CDKs. CHIR99021 functions as a Wnt/β-catenin activator and induces autophagy.