英文名称 | Thalidomide-4-OH | Cereblon ligand 2 | E3 ligase Ligand 2) |
---|---|
中文名称 | 2-(2,6-二氧代-3-哌啶基)-4-羟基异吲哚啉-1,3-二酮 |
CAS号 | 5054-59-1 |
分子式 | C13H10N2O5 |
分子量 | 274.23 |
MDL | MFCD03699892 |
外观 | White to gray powder |
储存条件 | 4°C, stored under nitroge |
英文名称 | Thalidomide-4-OH | Cereblon ligand 2 | E3 ligase Ligand 2) |
---|---|
中文名称 | 2-(2,6-二氧代-3-哌啶基)-4-羟基异吲哚啉-1,3-二酮 |
CAS号 | 5054-59-1 |
分子式 | C13H10N2O5 |
分子量 | 274.23 |
MDL | MFCD03699892 |
外观 | White to gray powder |
储存条件 | 4°C, stored under nitroge |
Thalidomide-4-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) can be connected to the ligand for protein by a linker to form PROTACs.