英文名称 | Cholera Toxin Subunit B(CTB); Cholera Toxin B Subunit (CTB) |
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中文名称 | 霍乱毒素亚型B(CTB) |
CAS号 | 131096-89-4 |
分子量 | 11kd |
外观 | White powder |
储存条件 | 2-8℃ |
英文名称 | Cholera Toxin Subunit B(CTB); Cholera Toxin B Subunit (CTB) |
---|---|
中文名称 | 霍乱毒素亚型B(CTB) |
CAS号 | 131096-89-4 |
分子量 | 11kd |
外观 | White powder |
储存条件 | 2-8℃ |
Cholera toxin belongs to the AB5 –subunit family oftoxins.The native hexameric protein has a molecular mass of ~85 kDa and contains two subunits. It consists of a single A subunit (~27.2 kDa), responsible for the ADP-ribosylation activity, and five B subunits(~11.6 kDa each), which are arranged as a pentameric ring with an apparent 5-fold symmetry and are associated with the cell surface receptor binding and subsequent internalization (transmembrane transport)of the enzymatic component.