英文名称 | Suplatast tosilate | IPD 1151T |
---|---|
中文名称 | 甲磺司特 |
CAS号 | 94055-76-2 |
分子式 | C23H33NO7S2 |
分子量 | 499.64 |
外观 | White to off-white powder |
储存条件 | 4°C, sealed storage, away from moisture |
英文名称 | Suplatast tosilate | IPD 1151T |
---|---|
中文名称 | 甲磺司特 |
CAS号 | 94055-76-2 |
分子式 | C23H33NO7S2 |
分子量 | 499.64 |
外观 | White to off-white powder |
储存条件 | 4°C, sealed storage, away from moisture |
Suplatast Tosilate (IPD 1151T) is an orally active Th2 cytokine inhibitor which can inhibit both IL-4 and IL-5 production from Th2 cells and suppress IgE synthesis. Suplatast Tosilate is an anti-allergic agent. Suplatast Tosilate has antiasthmatic, anti-inflammatory and antifibrotic activity.
PMID: 11817674 PMCID: PMC1781737 DOI: 10.1080/09629350120102352
Suplatast tosilate prevents bleomycin-induced pulmonary fibrosis in mice.
PMID: 18832650 DOI: 10.1124/jpet.108.141721