英文名称 | Gedatolisib | PKI-587 | PF-05212384 |
---|---|
中文名称 | 吉达利塞 |
CAS号 | 1197160-78-3 |
分子式 | C32H41N9O4 |
分子量 | 615.73 |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
英文名称 | Gedatolisib | PKI-587 | PF-05212384 |
---|---|
中文名称 | 吉达利塞 |
CAS号 | 1197160-78-3 |
分子式 | C32H41N9O4 |
分子量 | 615.73 |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Gedatolisib (PF-05212384, PKI-587) is a highly potent dual inhibitor of PI3Kα, PI3Kγ and mTOR with IC50 of 0.4 nM, 5.4 nM and 1.6 nM in cell-free assays, respectively. Phase 2.