英文名称 | Deruxtecan | DS-8201a | exatecan derivative | DX 8951; |
---|---|
中文名称 | 德鲁替康 |
CAS号 | 1599440-13-7 |
分子式 | C52H56FN9O13 |
分子量 | 1,034.05 |
外观 | White to yellow powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
英文名称 | Deruxtecan | DS-8201a | exatecan derivative | DX 8951; |
---|---|
中文名称 | 德鲁替康 |
CAS号 | 1599440-13-7 |
分子式 | C52H56FN9O13 |
分子量 | 1,034.05 |
外观 | White to yellow powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Deruxtecan is an ADC drug-linker conjugate composed of the cleavable glycine–glycine–phenylalanine–glycine tetrapeptide-based linker, a self-immolative amino methylene spacer, and a novel topoisomerase 1 inhibitor payload that is a derivative of exatecan (DX-8951).