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依喜替康甲磺酸盐|依沙替康甲磺酸盐

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Exatecan Mesylate (DX8951f)

产品编号:CL2725A CAS No.:169869-90-3 MDLNo: 分子式:C25H26FN3O7S 分子量:531.55
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基本信息
英文名称 Exatecan Mesylate (DX8951f)
中文名称依喜替康甲磺酸盐|依沙替康甲磺酸盐
CAS号169869-90-3
分子式C25H26FN3O7S
分子量531.55
外观Light yellow to green yellow powder
储存条件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
产品详情

 Exatecan, also known as DX 8951, is semisynthetic, water-soluble camptothecin derivative with antineoplastic activity. Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death. This agent does not require enzymatic activation and exhibits greater potency than camptothecin and other camptothecin analogues

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