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艾瑞昔布

Imrecoxib

产品编号：CL2697 CAS No.：395683-14-4 MDLNo： 分子式：C21H23NO3S 分子量：369.48

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基本信息

英文名称	Imrecoxib
中文名称	艾瑞昔布
CAS号	395683-14-4
分子式	C21H23NO3S
分子量	369.48
外观	White to off-white powder
储存条件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

产品详情

Imrecoxib, also known as BAP-909, a novel and selective cyclooxygenase 2 inhibitor with anti-inflammatory effect. Imrecoxib was found to inhibit COX-1 and COX-2 with IC50 value of 115+/-28 nmol/L and 18+/-4 nmol/L, respectively. Imrecoxib was shown to selectively and dose-dependently inhibit COX-2 mRNA level. Imrecoxib effectively inhibited carrageenan-induced acute inflammation at the doses of 5, 10, and 20 mg/kg i.g. and adjuvant-induced chronic inflammation at the doses of 10 and 20 mg/kg/d i.g.