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利特昔替尼对甲苯磺酸盐

Ritlecitinib Tosylate

产品编号:CL2693A CAS No.:2192215-81-7 MDLNo: 分子式:C22H27N5O4S 分子量:457.55
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基本信息
英文名称 Ritlecitinib Tosylate
中文名称利特昔替尼对甲苯磺酸盐
CAS号2192215-81-7
分子式C22H27N5O4S
分子量457.55
外观White to off-white powder
储存条件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
产品详情

 Ritlecitinib, also known as PF-06651600, is a potent and selective JAK3 inhibitor. PF-06651600 is a potent and low clearance compound with demonstrated in vivo efficacy. The favorable efficacy and safety profile of this JAK3-specific inhibitor PF-06651600 led to its evaluation in several human clinical studies. JAK3 was among the first of the JAKs targeted for therapeutic intervention due to the strong validation provided by human SCID patients displaying JAK3 deficiencies.


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