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马来酸茚达特罗; 茚达特罗马来酸盐

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Indacaterol Maleate

产品编号:CL2534A CAS No.:753498-25-8 MDLNo: 分子式:C28H32N2O7 分子量:508.56
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基本信息
英文名称 Indacaterol Maleate
中文名称马来酸茚达特罗; 茚达特罗马来酸盐
CAS号753498-25-8
分子式C28H32N2O7
分子量508.56
外观White to off-white powder
储存条件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
产品详情

Indacaterol Maleate (formerly known as QAB149; QAB-149; Onbrez Breezhale; arcapta neohaler; Onbrez), the maleate salt of indacaterol, is an approved anti-COPD (chronic obstructive pulmonary disease) drug acting as an ultra-long-acting β-adrenoceptor agonist developed by Novartis. β-adrenoceptor is activated with a pKi of 7.36 in. The FDA approved indacaterol in 2009 to treat chronic obstructive pulmonary disease (COPD). Using a dry powder inhaler, the aerosol formulation is administered. When Chinese hamster ovary cells are transfected with human β2 adrenoceptors and have a pEC50 of 8.06, indacaterol inhibits the production of cAMP.

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