PF-04620110

规格	库存	目录价	会员专享价	数量
5 mg	3-5days	￥550.00	登录后可见	- +
10 mg	3-5days	￥800.00	登录后可见	- +
25 mg	3-5days	￥1460.00	登录后可见	- +

规格

库存

目录价

会员专享价

数量

5 mg

3-5days

￥550.00

登录后可见

- +

10 mg

3-5days

￥800.00

登录后可见

- +

25 mg

3-5days

￥1460.00

登录后可见

- +

基本信息

英文名称	trans-4-[4-(4-Amino-7,8-dihydro-5-oxopyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl]-cyclohexaneacetic acid
中文名称	PF-04620110
CAS号	1109276-89-2
分子式	C21H24N4O4
分子量	396.44
外观	White to off-white powder
储存条件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

产品详情

PF-04620110 (PF04620110; PF 04620110) is a novel, potent, orally bioactive, and selective diglyceride acyltransferase-1 (DGAT1) inhibitor with the potential to treat type 2 diabetes mellitus. It inhibits DGAT1 with an IC50 of 19 nM. PF-04620110 has been advanced to clinical trials on the basis of the excellent pharmacologic and pharmacokinetic profiles. F-04620110 shows high selectivity versus a broad panel of off-target pharmacologic end points. In vivo DGAT-1 inhibition has been demonstrated through reduction of plasma triglyceride levels in rodents at doses of ≥0.1 mg/kg following a lipid challenge.

PF-04620110

trans-4-[4-(4-Amino-7,8-dihydro-5-oxopyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl]-cyclohexaneacetic acid

化学品安全说明书(MSDS)