Torin 2

规格	库存	目录价	会员专享价	数量
5 mg	3-5days	￥620.00	登录后可见	- +
10 mg	3-5days	￥950.00	登录后可见	- +
25 mg	3-5days	￥1660.00	登录后可见	- +

规格

库存

目录价

会员专享价

数量

5 mg

3-5days

￥620.00

登录后可见

- +

10 mg

3-5days

￥950.00

登录后可见

- +

25 mg

3-5days

￥1660.00

登录后可见

- +

基本信息

英文名称	Torin 2
中文名称	9-(6-氨基吡啶-3-基)-1-(3-(三氟甲基)苯基)苯并[H][1,6]萘啶-2(1H)-酮
CAS号	1223001-51-1
分子式	C24H15F3N4O
分子量	432.40
外观	White to light yellow powder
储存条件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

产品详情

Torin-2 is a novel, second-generation ATP-competitive inhibitor that is potent and selective for mTOR with a superior pharmacokinetic profile to previous inhibitors ((EC50 = 0.3 nM). It has been shown that Torin-2 displayed dramatic antiproliferative activity across a panel of cancer cell lines. Torin-2 showed a powerful cytotoxic activity, inhibiting the growth of each cell line in a dose-dependent manner, with an IC₅₀ in the nanomolar range. Torin-2 caused both apoptosis and autophagy, induced cell cycle arrest in G₀/G₁ phase and affected both mTORC1 and mTORC2 activities.

9-(6-氨基吡啶-3-基)-1-(3-(三氟甲基)苯基)苯并[H][1,6]萘啶-2(1H)-酮

Torin 2

化学品安全说明书(MSDS)