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康普瑞汀磷酸二钠

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Combretastatin A4 Disodium Phosphate(CA4P)

产品编号：CL2386 CAS No.：168555-66-6 MDLNo： 分子式：C18H19PO8Na2 分子量：440.29

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规格	库存	目录价	会员专享价	数量
10 mg	In-stock	￥700.00	登录后可见	- +
20 mg	In-stock	￥1120.00	登录后可见	- +
50 mg	In-stock	￥2200.00	登录后可见	- +

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基本信息

英文名称	Combretastatin A4 Disodium Phosphate(CA4P)
中文名称	康普瑞汀磷酸二钠
CAS号	168555-66-6
分子式	C18H19PO8Na2
分子量	440.29
外观	white powder
储存条件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

产品详情

Fosbretabulin (Combretastatin A4 Phosphate, CA4P, CA 4DP) Disodium is the water-soluble prodrug of Combretastatin A4 (CA4), which is a microtubule-targeting agent that binds β-tubulin with Kd of 0.4 μM in a cell-free assay. Fosbretabulin Disodium inhibits the polymerization of tubulin with IC50 of 2.4 μM, and also disrupts tumor vasculature. Fosbretabulin disodium induces mitotic arrest and apoptosis in endothelial cells. Phase 3.