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吡非尼酮

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Pirfenidone (AMR69)

产品编号:CL2376 CAS No.:53179-13-8 MDLNo: 分子式:C12H11NO 分子量:197.33
规格 库存 目录价 会员专享价 数量
500 mg In-stock ¥480.00 登录后可见
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1 g In-stock ¥680.00 登录后可见
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基本信息
英文名称 Pirfenidone (AMR69)
中文名称吡非尼酮
CAS号53179-13-8
分子式C12H11NO
分子量197.33
外观White to light yellow powder
储存条件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
产品详情

Pirfenidone is an anti-fibrotic drug for the treatment of idiopathic pulmonary fibrosis (IPF). It works by reducing lung fibrosis through downregulation of the production of growth factors and procollagens I and II. Pirfenidone has well-established antifibrotic and anti-inflammatory properties in various in vitro systems and animal models of fibrosis. A number of cell-based studies have shown that pirfenidone reduces fibroblast proliferation, inhibits TGF-β stimulated collagen production and reduces the production of fibrogenic mediators such as TGF-β.

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