Saracatinib(AZD0530)

规格	库存	目录价	会员专享价	数量
10 mg	In-stock	￥466.00	登录后可见	- +
25 mg	In-stock	￥688.00	登录后可见	- +

规格

库存

目录价

会员专享价

数量

10 mg

In-stock

￥466.00

登录后可见

- +

25 mg

In-stock

￥688.00

登录后可见

- +

基本信息

英文名称	Saracatinib(AZD0530)
中文名称	塞卡替尼
CAS号	379231-04-6
分子式	C27H32ClN5O5
分子量	542.03
外观	White to light yellow powder
储存条件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

产品详情

Saracatinib, also known as AZD0530, is an orally available dual-specific inhibitor of Src and Abl with anti-invasive and anti-tumor activities. Src and Abl are protein tyrosine kinases that are overexpressed in chronic myeloid leukemia cells. Saracatinib binds to and inhibits these tyrosine kinases and their effects on cell motility, cell migration, adhesion, invasion, proliferation, differentiation, and survival.

Saracatinib (AZD0530) is a potent Src family inhibitor with IC50s of 2.7 to 11 nM for c-Src, Lck, c-YES, Lyn, Fyn, Fgr, and Blk. Saracatinib shows high selectivity over other tyrosine kinases.

塞卡替尼

Saracatinib(AZD0530)

化学品安全说明书(MSDS)

质检证书(COA)