Everolimus | RAD-001 | 依维莫司

规格	库存	目录价	会员专享价	数量
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规格

库存

目录价

会员专享价

数量

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基本信息

英文名称	Everolimus \| RAD-001
中文名称	依维莫司
CAS号	159351-69-6
分子式	C53H83NO14
分子量	958.22
外观	White to off-white powder
储存条件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

产品详情

Everolimus, also known as RAD001, is a derivative of the natural macrocyclic lactone sirolimus with immunosuppressant and anti-angiogenic properties. In cells, everolimus binds to the immunophilin FK Binding Protein-12 (FKBP-12) to generate an immunosuppressive complex that binds to and inhibits the activation of the mammalian Target of Rapamycin (mTOR), a key regulatory kinase. Inhibition of mTOR activation results in the inhibition of T lymphocyte activation and proliferation associated with antigen and cytokine (IL-2, IL-4, and IL-15) stimulation and the inhibition of antibody production.

依维莫司

Everolimus | RAD-001

化学品安全说明书(MSDS)