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甲氨蝶呤

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Methotrexate

产品编号：CL2266 CAS No.：59-05-2 MDLNo： 分子式：C20H22N8O5 分子量：454.44

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规格	库存	目录价	会员专享价	数量
250 mg	In-stock	￥500.00	登录后可见	- +
500 mg	In-stock	￥800.00	登录后可见	- +
1 g	In-stock	￥1280.00	登录后可见	- +

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基本信息
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基本信息

英文名称	Methotrexate
中文名称	甲氨蝶呤
CAS号	59-05-2
分子式	C20H22N8O5
分子量	454.44
外观	Light yellow to yellow powder
储存条件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

产品详情

Methotrexate (MTX; alphamethopterin; amethopterin; methylaminopterin; CL-14377; NCIC04671; WR19039; NCI-C04671) is an FDA approved antineoplastic and immunosuppressant drug that belongs to the antimetabolite and antifolate class of drugs. It acts by inhibiting the metabolism of folic acid in activated peripheral T cells. Specifically, methotrexate binds to and inhibits the enzyme dihydrofolate reductase, resulting in inhibition of purine nucleotide and thymidylate synthesis and, subsequently, inhibition of DNA and RNA syntheses. Methotrexate (Amethopterin) is the disease-modifying antirheumatic drug (DMARD) of first choice for the treatment of RA in most countries worldwide. Methotrexate is an antineoplastic agent used to fight a number of different cancers, such as acute lymphoblastic leukemia and solid cancers.