英文名称 | Pirarubicin |
---|---|
中文名称 | 吡柔比星 | 吡喃阿霉素 | 吡柔吡星 |
CAS号 | 72496-41-4 |
分子式 | C32H37NO12 |
分子量 | 627.64 |
外观 | Pink to red powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
英文名称 | Pirarubicin |
---|---|
中文名称 | 吡柔比星 | 吡喃阿霉素 | 吡柔吡星 |
CAS号 | 72496-41-4 |
分子式 | C32H37NO12 |
分子量 | 627.64 |
外观 | Pink to red powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Pirarubicin is an anthracycline drug. An analogue of the anthracycline antineoplastic antibiotic doxorubicin. Pirarubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent is less cardiotoxic than doxorubicin and exhibits activity against some doxorubicin-resistant cell lines.