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无水多西他赛

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Docetaxel Anhydrous

产品编号:CL1064 CAS No.:114977-28-5 MDLNo: 分子式:C43H53NO14 分子量:807.88
规格 库存 目录价 会员专享价 数量
100 mg In-stock ¥150.00 登录后可见
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200 mg In-stock ¥250.00 登录后可见
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500 mg In-stock ¥450.00 登录后可见
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基本信息
英文名称 Docetaxel Anhydrous
中文名称无水多西他赛
CAS号114977-28-5
分子式C43H53NO14
分子量807.88
外观White or almost white, crystalline, hygroscopic powder
储存条件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
产品详情

      Docetaxel, an analog of paclitaxel, is an inhibitor of depolymerisation of microtubules by binding to stabilized microtubules.    


     Docetaxel is a microtubule-stabilizing agent and a semisynthetic derivative of paclitaxel.It promotes microtubule assembly in a cell-free assay when used at a concentration of 20 µM and is cytotoxic to J774.2 cells (EC50 = 0.05 µM).In vivo, docetaxel inhibits tumor growth in several cancer models, including B16 murine melanoma and P388 murine leukemia models. Formulations containing docetaxel have been used in the treatment of head and neck, breast, and non-small cell lung cancer, gastric adenocarcinoma, and castration-resistant prostate cance


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