Y-27632 Dihydrochloride; Y-27632 2HCl

规格	库存	目录价	会员专享价	数量
5 mg	In-stock	￥650.00	登录后可见	- +
10 mg	In-stock	￥900.00	登录后可见	- +
25 mg	In-stock	￥1600.00	登录后可见	- +
50 mg	In-stock	￥2800.00	登录后可见	- +

规格

库存

目录价

会员专享价

数量

5 mg

In-stock

￥650.00

登录后可见

- +

10 mg

In-stock

￥900.00

登录后可见

- +

25 mg

In-stock

￥1600.00

登录后可见

- +

50 mg

In-stock

￥2800.00

登录后可见

- +

基本信息

英文名称	Y-27632 Dihydrochloride; Y-27632 2HCl
中文名称	反式-4-[(R)-1-氨基乙基]-N-(4-吡啶基)环己烷甲酰胺二盐酸盐
CAS号	129830-38-2
分子式	C14H21N3O.2HCl
分子量	320.26
外观	White to off-white solid powder

产品详情

The ROCK family of Rho-associated serine-threonine protein kinases is known to play an important role in Rho-mediated cell adhesion and smooth muscle contraction. Y-27632 is a potent, ATP-competitive inhibitor of ROCKs including p160ROCK (Ki = 140 nM) and ROCK2 (IC50 = 800 nM). It also inhibits PRK2 with an IC50 value of 600 nM. One-hour treatment with 10 µM Y-27632 blocks apoptosis of dissociated cultured human embryonic stem cells, increasing cloning efficiency by 25% and sustaining survival up to 30 passages.

反式-4-[(R)-1-氨基乙基]-N-(4-吡啶基)环己烷甲酰胺二盐酸盐

Y-27632 Dihydrochloride; Y-27632 2HCl

化学品安全说明书(MSDS)

质检证书(COA)