英文名称 | Tipranavir(TPV) |
---|---|
中文名称 | 替拉那韦 |
CAS号 | 174484-41-4 |
分子式 | C31H33F3N2O5S |
分子量 | 602.66 |
外观 | White to off-white powder |
储存条件 | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
英文名称 | Tipranavir(TPV) |
---|---|
中文名称 | 替拉那韦 |
CAS号 | 174484-41-4 |
分子式 | C31H33F3N2O5S |
分子量 | 602.66 |
外观 | White to off-white powder |
储存条件 | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Tipranavir is a protease inhibitor that inhibits HIV-1 resistant to more than 1 protease inhibitor .Tipranavir effectively inhibits HIV-1 protease enzyme activity and dimerisation and has potent activity against multiple protease inhibitor (PI) HIV-1 isolates (IC50 of 66-410 nM). Tipranavir inhibits SARS-CoV-2 3CLpro activity.